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When properly prepared, it may be used in specialized applications under the guidance of a qualified healthcare professional
10.1074/jbc.M707951200 J
10.3390/microorganisms9102141 135 KaoreS
Mechanistically, autoantibodies and interferon- present in the serum induce neutrophil ferroptosis through enhanced binding of the transcriptional repressor CREM to the glutathione peroxidase 4 ( Gpx4 , the key ferroptosis regulator) promoter, which leads to suppressed expression of Gpx4 and subsequent elevation of lipid-reactive oxygen species
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