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IGF-1 DES exhibits moderate side effects, low oral and excellent subcutaneous bioavailability in mice
Adults with longevity and biological aging optimization goals who want a foundational anti-aging intervention alongside other longevity peptides and lifestyle protocols Patients with age-related sleep deterioration and circadian rhythm disruption who have not responded adequately to standard sleep interventions Patients with documented age-related decline in multiple biological markers (antioxidant capacity, immune function, hormonal balance) for whom a broad-spectrum bioregulator approach is appropriate Patients already engaged in comprehensive longevity protocols (NMN, GH secretagogues, NAD+ optimization) who want to add a pineal-axis and telomere-focused component Patients over 45 to 50 where age-related biological decline provides the clinical rationale for a geroprotective intervention The cancer contraindication for Epitalon requires specific attention in the clinical assessment
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In contrast, peptides improve protein synthesis and tissue repair
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