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In order to test this possibility, we engineered a murinized version of the anti-IGF-1R mAb, L2-C (L2-Cmu), in order to reduce effector function and enable chronic administration in mice
The surgery group had 30% lower mortality risk, 72% diabetes remission rates at two years, and substantial reductions in cardiovascular events
In this laboratory study, scientists used a cell model to mimic the effects of Alzheimers disease on brain cells
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