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We were delighted to find that 23 was still active (3.4 nM) with a similar potency to 14 , considering that 25% of the GLP-1 sequence was replaced by oligoureas
As a fellow manufacturer, I understand that this tone is not only marketing language
The 0.2 mg SAR425899 dose was the highest safe dose tested so far in humans and considered the target dose for late stage clinical development
This time spent was in addition to the thousands of hours our team has already devoted to researching therapeutic peptides over the last year or so
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