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Subsequently, GSH ester (100 M) was added to replenish the intracellular GSH loss, which led to recovery of GSH to the basal level in the next 3 min, as recorded by RT (Fig

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Partial Least Squares-Discriminant Analysis (PLS-DA) is a supervised discriminant statistical method that uses partial least squares regression to model the relationship between metabolite expression and sample grouping to achieve prediction of the sample category