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It reflects the point at which benzyl alcohol's antimicrobial efficacy drops below sterile threshold and peptide aggregates begin forming even at refrigerated temperatures

In the 12 mg dose group, 16% of subjects discontinued due to adverse events (AEs), but the overall incidence of severe adverse events (SAEs) was low, about 6%-8%

[3] Treatment is by vitamin B 12 supplementation, either by mouth or by injection

Increased Epididymal levels of glutathione (GSH) (part of the male reproductive tract, where sperm final maturation occurs) can protect the sperm membrane PUFA, playing a protective role in sperm maturation