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Acknowledgements The study was supported by the NIHR Oxford Health Biomedical Research Centre (NIHR203316) and the UKRI (MR/T033371/1 and MR/K022202)

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Dysautonomia and POTS: The active Vitamin B6 (P-5-P) in the formula is required to synthesize GABA, an inhibitory neurotransmitter that helps calm the overactive sympathetic nervous system, potentially easing the rapid heart rate and adrenaline surges associated with dysautonomia

GLP-1 plays a critical role in regulating blood sugar levels by stimulating insulin secretion from the pancreas after meals, slowing gastric emptying, and reducing appetite