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These studies indicate the potential of utilizing the de novo pathway, a less extensively studied pathway, as a therapeutic strategy for metabolic diseases Barth syndrome is a rare disease caused by mutations in the tafazzin gene encoding for cardiolipin (CL), a phospholipid specific for the mitochondria 303

The same case report documented biological age reduction and telomere length increase, with the patient's biological age decreasing by 7.9 years (from 75.93 to 68.03) and telomere length increasing from 6.45 to 6.59 kb over one year of treatment

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