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Probiotics, in particular, offer multifaceted benefits by restoring microbial balance, producing SCFAs that enhance intestinal barrier integrity (181), and modulating immune responses via Toll-like receptor (TLR) signaling (182)

As a general procedure, the investigators directly performing the experimental procedures were not blinded to the group allocation, but data analyses by senior authors were largely conducted independently to avoid potential bias

2011;5(3):e998