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In addition to steatosis, NASH is characterized by inflammation, ballooning degeneration, and fibrosis, which ultimately leads to liver fibrosis and end-stage cirrhosis ( Materials and methods Animal model Male C57BL/6J mice (6 weeks old) were purchased from Hebei Ivivo Biotechnology Co., Ltd
& Du, J
The medication reaches steady-state concentrations after approximately four to five weeks of regular dosing, creating a stable therapeutic effect
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