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Clinical trials using combinations of CoQ10 with cross-linked hyaluronic acid (XL-HA) have shown enhanced treatment outcomes in DED patients, attributed to CoQ10s antioxidant effects and HAs inherent water retention and viscoelasticity properties, which are essential for repairing ocular tissues (Postorino et al., 2018

STEP and SURMOUNT trials didnt standardize specific injection times, and post-hoc analyses found no differences in efficacy by time of day

Dapagliflozin once-daily and exenatide once-weekly dual therapy: a 24-week randomized, placebo-controlled, phase II study examining effects on body weight and prediabetes in obese adults without diabetes

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