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This suggests that GLP-1 may be a promising therapeutic target for neurodegenerative diseases such as Alzheimers ( Current research also confirmed the possible interaction among AMPK/SIRT1, autophagy and NLRP3 inflammatory corpuscle pathway and their role in the potential anti-inflammatory neuroprotective effect of Liraglutide ( In conclusion, GLP-1 improves cognitive function by engaging multiple signaling pathways, including CREB, PI3K/Akt, mTOR, and SIRT1

On the other hand, TZT, through activation of the GLP-1 receptor, may produce beneficial effects against Covid-19 severity

The current data showing that GLP-1 drugs may lower cancer risk are from retrospective studies , which means researchers looked back at medical records of patients who were taking GLP-1s for other reasons and tracked who developed cancer

immediate-release formulations are generally preferred in this population [12]