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The accumulation of these metabolites has been shown to inhibit -KDD activity (most likely due to -KG depletion), thereby promoting stem cell differentiation [107, 108]
It could increase access to obesity and diabetes treatment, especially in low-resource settings
TL;DR GLP-1 drugs such as semaglutide, tirzepatide, and liraglutide can help reduce appetite and body weight, but emerging research shows they may also increase the risk of protein, vitamin, and mineral deficiencies, especially when appetite drops sharply and food intake becomes too low or too limited
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