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10.1016/s1535-6108(04)00115-1 53 MuthukumarK.RajakumarS.SarkarM

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Moreover, the relationship between UA levels and MS-related disability suggests that UA could be a good biomarker of MS disability and progression [159, 160]

It has since become an important subject of research involving sleep regulation pathways, neuroendocrine signalling, circadian rhythm biology, stress-response mechanisms, hormonal regulation, and central nervous system function