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Tirzepatide works as a dual agonist, meaning it activates two specific receptors
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The duration problem might be mitigated via coadministration with a PDE5 inhibitor, which yielded good results in a small 2005 study.8 Yet research on this approach remains limited
National Library of Medicine , "FDA Approves Ozempic (Semaglutide) as the Only GLP-1 RA to Reduce the Risk of Worsening Kidney Disease and Cardiovascular Death in Adults with Type 2 Diabetes and Chronic Kidney Disease." PR Newswire , "FDA Approves Wegovy (Semaglutide) for Adults with Obesity." Drugs.com , 2021, Fonseca, Vivian A., et al
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