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Current safety data for 5-amino-1MQ appears favorable for short-term use (8-12 week cycles), with no significant toxicity observed in preclinical studies at therapeutic doses
Moreover, the use of iron chelators and other compounds that can modulate the ferroptosis pathway could provide a novel therapeutic approach for ichthyosis
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Improve red blood cell production
Although this GST was also present in a near isogenic susceptible line, evaluation of corresponding transcript accumulation revealed that GST gene expression was significantly induced only in the BNYVV-resistant line (Larson et al., 2008)
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