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Enrichment of RNA sequencing data indicated that the Wnt/LRP5/-catenin pathway was activated after treatment with semaglutide
It drives the transition from proliferation to differentiation and increases the number and length of multinucleated myotubes in a dosedependent manner.The mechanism is mainly related to NNMT inhibition, restored NAD levels, and activation of the SIRT1PGC1 pathway
Existing conditions, current medications, and potential contraindications are reviewed carefully, particularly when a treatment affects appetite and metabolic pathways
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Yang D, Yang J, Shi D, Xiao D, Chen YT, Black C, et al
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