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The NHS recommends adequate fluid intake, which may help with overall tolerance, particularly if experiencing gastrointestinal side effects
and U.K., is not as tightly regulated as pharmaceuticals," agrees Dr Khan
Right now, there are two studies that can shed some light on this: Controlled lab trial (JAMA Psychiatry, 2025) Researchers gave weekly semaglutide injections to 48 adults diagnosed with Alcohol Use Disorder (AUD), meaning they drank at least 7 drinks per week (women) or 14 drinks per week (men), and had at least two heavy-drinking episodes per month (4+ drinks per sitting for women, 5+ for men)
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