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In August, Rybrevant was approved in combination with lazertinib for the first-line treatment of locally advanced or metastatic NSCLC with EGFR exon 19 deletions or L858R substitution mutations
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The agency said it is intended to address a gap in managing impurities for such antibiotics, since current guidance does not address controlling impurities or their degradation (RELATED: FDA draft guidance sets impurity controls for most antibiotics , Regulatory Focus, 20 April 2026)
Transcriptional regulation of the human cystathionine beta-synthase -1b basal promoter: synergistic transactivation by transcription factors NF-Y and Sp1/Sp3
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