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Materials and methods Ethical approval This study was approved by the Life Science Ethics Committee of Zhengzhou University (Permit code

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1 Introduction Diabetes is a metabolic disease that poses a serious threat to human health ( At present, the molecular mechanism of diabetic cognitive dysfunction has not been elucidated, and it may involve multiple factors, such as oxidative stress, neuroinflammation, endothelial cell dysfunction, etc ( The utilization of plant-derived phytochemicals for disease intervention has increasingly become a focal point in contemporary research

USA 106 , 422427 (2009)