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Ongoing phase 3 clinical trials are testing the medication for weight management, osteoarthritis, NAFLD, cardiovascular risk reduction, type 2 diabetes, and moderate to severe obstructive sleep apnea in obese and overweight patients
It supports gut health, reduces inflammation, and promotes tissue healing
TXNIP: thioredoxin-interacting protein
These recommendations are very consistent with the key points from the most current international guidelines, especially those published, in 2024 and 2025, by multi-society groups in both the US and the UK 1-3
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