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The same caloric reduction that produces healthy weight loss in a middle-aged adult can accelerate muscle loss in a senior, a condition called sarcopenia that already worsens naturally with age

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When activated with GLP-1r, GIP seems to potentiate not only the weight loss mechanism of the incretin but also the glucose lowering effects [13]

And so it's kind of, if you think about dropping an Alka-Seltzer tablet in a glass of water, that immediate fizzy reaction that occurs, that is what happens in stomach as soon as this tablet hits the base of your stomach, hits that stomach wall