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Note that DPP-4 inhibitors should not be used concurrently with GLP-1 receptor agonists due to overlapping mechanisms
in both studies, it showed promising potential against epilepsy
It may increase creatinine levels without causing damage to renal function: in trained athletes, creatinine supplementation for 3 months had no detrimental effects on renal function, measured by 51 Cr-EDTA.20 The problem is that, in this context, an elevation of serum creatinine may reflect creatine supplementation or a real kidney damage, and the nephrologist must differentiate both situations by calculating the 24h creatinine clearance
Paradoxically, a reduction in common tirzepatide side effects like nausea, constipation , or digestive changes after a suspected heat event could indicate reduced potency
