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each excursion outside the recommended range may cumulatively reduce stability Never attempt to use a product that has been frozen freezing is likely to have caused irreversible structural damage When in doubt, the safest course of action is to discard the product and obtain a replacement through the appropriate clinical or dispensing channel, following the IMP protocol
LUPKIN: During an official shortage, compounding pharmacies aren't limited to mixing up custom medicines
You can view more specific information on the official website for each medication, or you can talk to your doctor about them
Dose-by-dose weight loss in Phase 2 (NEJM) Phase 2 NEJM weight loss by dose, 24 and 48 weeks Dose 1 mg 24 weeks -7.2% 48 weeks -8.7% Dose 4 mg 24 weeks -12.9% 48 weeks -17.5% Dose 8 mg 24 weeks -15.7% 48 weeks -22.8% Dose 12 mg 24 weeks -17.5% 48 weeks -24.2% Dose Placebo 24 weeks -1.6% 48 weeks -2.1% Source: Jastreboff et al., NEJM 2023
