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A patient on a GLP-1 plus a PPI faces two separate mechanisms of magnesium depletion: reduced absorption and increased GI losses

*Compounded medications may be prescribed by physicians, but have not been FDA-regulated for safety, effectiveness, or quality

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Other significant factors include genetic variations, nutritional deficiencies of cofactors (copper, zinc, manganese), overwhelming oxidative stress, and inflammatory conditions that alter SOD expression or activity