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10.1016/j.cbi.2025.111459 73 LvR.LiuB.JiangZ.ZhouR.LiuX.LuT.et al (2025)

When no applicable USP/NF monograph exists and the substance is not a component of an approved drug, appearing on the 503A Bulks List can satisfy one of the conditions governing use of that bulk substance

Further, brain cells are unable to swell due to the rigidity of the skull [19]