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Another prospective, observational study analysed the changes in health-related quality of life and emotional well-being in patients who had commenced GLP-1 analogue therapy (exenatide) in comparison with new insulin starters
By binding to p53, it induces nuclear exclusion, allowing p53 to translocate to the cytoplasm and mitochondria, subsequently activating the p53/BCL-2/Caspase-3 signaling pathway to execute selective apoptosis in senescent populations (Frontiers, 2025
Although relative risk estimates varied slightly across studies, absolute event rates remained very low in all groups
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