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Numerous studies have shown that genomic DNA methylation patterns are significantly remodeled during aging, and DNA methylation levels at specific CpG sites can predict the aging status of cells (Dozmorov et al., 2017)

Glutathione optimization is most appropriate for patients with documented biomarker deficiency, high oxidative stress (elevated oxidized glutathione or inflammatory markers), metabolic dysfunction, or chronic health conditions

Bjermer, L., Lundgren, R

Elastin fibers are damaged and have limited capacity to regenerate naturally (adult humans produce very little new elastin after puberty under normal conditions)