Heart and kidney health and GLP-1s The reason that medical experts recommend weight loss to certain people in the first place is because having overweight or obesity is linked to a higher risk for serious health issues
Patients with elevated WHR but lower BMI had higher NYHA functional class and N-terminal proB-type natriuretic peptide, poorer kidney function, and lower 6MWD compared with those with lower WHR but higher BMI
From a practical standpoint, the most defensible position remains planned exposure avoidance: explicit fertility planning, reliable contraception during treatment, label-informed discontinuation before conception attempts, immediate cessation once pregnancy is recognized, and active metabolic maintenance during the washout period to reduce rebound-related gestational risk (45, 132137)
Key topics to discuss include: Your current medications Provide a complete list of all prescription medications, over-the-counter drugs, and supplements you take