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Overall, the GHGHRIGF1 axis, part of the somatotropichypothalamicpituitary axis, has been commonly recognized in response to somatic growth, including cell proliferation, differentiation, division, and survival (Figure 1)
However, lets look a little past the convenience
Obesity (Silver Spring) 26(2):284290 Packer M, Kitzman DW (2018) Obesity-related heart failure with a preserved ejection fraction: the mechanistic rationale for combining inhibitors of aldosterone, neprilysin, and sodium-glucose cotransporter-2
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