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The Scripps Research LoCITT-T trial is investigating exactly this question

Overall Health CJC-1295 + Ipamorelin: Oral Spray vs Nasal vs Injection Bioavailability, Delivery, and Practice Fit Newtropin The Growing Delivery-Options Conversation CJC-1295 and ipamorelin used individually and in combination are among the most widely prescribed peptide therapies in physician practice

As most GLP-1s require prior authorization for insurance coverage, it is likely you will need it