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We cant assume right off the bat that the pain in the stomach region is always stomach pain, says Tamara Duker Freuman, MS, RD, CDN, a registered dietitian specializing in digestive and metabolic diseases
Oral tablets, especially with absorption issues, offer much lower and more variable bioavailability, working more slowly
Serious side effects of the medication include the following: Allergic or hypersensitivity reaction Severe gastrointestinal issues Changes in mood and behavior Pancreatitis Liver problems Low blood sugar levels (hypoglycemia) Cardiac arrhythmias Suicidal ideation Major depressive disorder No adverse event of hypoglycemia or thyroid cancer was reported in Phase II trials, and 7% of retatrutide participants had skin sensitivity, compared to 1% on placebo, but these cases were not serious
