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This randomized controlled trial demonstrates that 28 days of vitamin B complex supplementation significantly improved exercise endurance and reduced fatigue-related biomarkers in healthy adults

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System Xc-passes through a heterodimer of the light-chain subunit SLC7A11 and the heavy-chain subunit SLC3A2, and glutamate-cysteine ligase (GCL) and glutathione synthase (GSS) transfer cystine to the cell and synthesise glutathione (GSH)

And the same mechanism that contributes to the reduced appetite that supports weight loss has recently been identified as having strong potential to disrupt the relationship between addiction, so much so as to reduce or altogether eliminate drug cravings