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Clinical trials show that nausea affects approximately 44% of patients taking semaglutide (Wegovy) and about 24-40% of those on tirzepatide (Zepbound), with rates varying by dose
therefore, we can assume that our observations were the result of local GLP-1R stimulation and not the result of feed-forward circuit-level changes
Semaglutide, however, works by controlling appetite and helping people feel full faster, which can lead to weight loss
In a research letter published in JAMA Network Open in August, the authors purchased off-brand forms of semaglutide from six online pharmacies
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