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The biggest drug category in a generation may need a second drug to complete the prescription
In an observational study of patients denied TKA because of an institutional BMI cutoff, only 19.1% reached a BMI below 40 kg/m 2 within 2 years in the absence of dedicated weight-loss protocols, whereas 53.1% neither underwent TKA nor became eligible during follow-up (Wilson et al., 2022)
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Table 2 Clinical evidence GLP-1 receptor agonists, reported adverse effects and taste perception
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