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Further, activation of the NLRP3 cascade promotes RF through RTEC pyroptosis ( SalB enhances the nuclear accumulation of Nrf2 and suppresses NLRP3 activation, oxidative stress, and Caspase-1/Gasdermin D-mediated cellular pyroptosis via the Nrf2/NLRP3 pathway (Pang et al., 2020)
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Ipamorelin is a synthetic pentapeptide classified as a growth hormone secretagogue receptor agonist and ghrelin mimetic
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