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You may have circulation problems if your fingers and toes feel cold or numb or if your skin turns blue or red

While reactive oxygen species such as superoxide are a normal byproduct of energy production in mitochondria, superoxide radicals generated by glucose overload may cause diabetic complications (Giacco 2010

Several studies showed evident association between type II diabetes and cancer, in particular in liver and pancreas, organs persistently exposed to high levels of endogenous insulin 117,118,119

Sikiric P., Seiwerth S., Rucman R., Drmic D., Stupnisek M., Kokot A., Sever M., Zoricic I., Zoricic Z., Batelja L., et al