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Fingolimod, a drug which first arose due its role on lymphocyte migration, showed the ability to induce angiogenesis by inducing a M2 phenotype in microglia through S1PR1 modulation (158) and STAT3 signaling (159)
and A.S analyzed data
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For emerging peptides, patients should ask what kind of evidence supports the proposed use
Whilst some patients would prefer injections to skin patches or nasal sprays to sub-lingual tablets or sprays others might, and this already happens in a few cases, they might prefer daily oral tablets
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