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This hypothesis was supported in a recent study with a 20-year follow-up, which found chronic low dose exposure to POPs predicted excess adiposity, dyslipidemia, and insulin resistance among participants without diabetes, in a U-shaped fashion (characteristic of endocrine disruption)
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However, a potential limitation of the work is that other alternative sources of amino acids, including cysteine, may exist in the tumour interstitial fluid, and their relative contribution has not yet been defined
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