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The decision to initiate pharmacotherapy requires shared decision-making, discussing realistic expectations, potential adverse effects, cost considerations, and the likely need for indefinite treatment duration

The initial response of both the Canadian Anesthesiologists Society (CAS) and the American Society of Anesthesiologists (ASA), similar to a topical Editorial in the Journal , was that of caution despite limited data as to the scope of the problem

Additional limitations were minimal BD data

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