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Similar to metformin, empagliflozin activates the AMPK signalling pathway, inhibits Drp1S616 phosphorylation, increases Drp1S637 phosphorylation, inhibits mitochondrial fission and subsequently prevents CMECs senescence by inhibiting mitochondrial ROS production, thereby increasing the viability and barrier performance of CMECs
Softw 82 , (2017)
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