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[9] Because B vitamins are water-soluble, excess amounts are excreted in urine, which can lead to a noticeable change in urine color

Over time, however, the treatment effect of a marginal 30-week regimen dissipated

Further, African green monkeys with pre-existing antibody and/or T cells after primary SARS-CoV infection were protected from homologous re-challenge as assessed by lung virus titres, although the pulmonary inflammatory response was not different from that of primary infection 128

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