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Hence, MTs impact on cellular proliferation could be more pronounced in TRIP13 KO cells because these cells might have an already destabilized genomic state, making them more susceptible to the effects of MT

These exacerbated inflammatory responses entail upregulation of the angiotensin-converting enzyme-2 (ACE2) receptor, to which the SARS-CoV-2 virus spike protein (S protein) binds, thereby gaining entry to host cells (11, 13)

The widespread use of these drugs for weight loss has sparked debates as to the medicalisation of obesity and the ethics of using pharmaceuticals for body modification (Arillotta et al., 2023)