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This breakdown results in a pathological state marked by the aberrant upregulation of MHC class I and II molecules and the increased expression of NKG2D ligandsparticularly MICA and ULBPon the epithelial cells of the hair follicle

The major transcription factors regulating transcription of genes encoding PPP enzymes in response to increased anabolic metabolism, particularly increased lipid synthesis, are members of the sterol regulated element binding protein (SREBP) family

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Interactions between foods and oral or injectable forms of methylcobalamin are not expected