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Record lot identifiers in laboratory notebooks before reconstitution
Make a note of what happened and return to your regular schedule with the next dose
Foundational work from the de Keizer laboratory (Baar et al., Cell, 2017) reported that the peptide perturbs the FOXO4-p53 association, leading to p53 nuclear exclusion and apoptosis that appeared preferential to senescent cells in cultured cells and aged mouse models
Its important to understand how they work and where they come from
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