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In one study 10 , elderly mice treated with 5-Amino-1MQ showed: ~40% stronger grip strength in sedentary conditions ~20% improvement with exercise ~60% boost when combined with exercise + therapy This suggests powerful benefits for maintaining strength and resilience with age
Increases in resting heart rate are a recognised class effect of incretin-based therapies and have been reported with GLP-1 receptor agonists more broadly, as reflected in the Summary of Product Characteristics (SmPC) for licensed agents such as semaglutide (Wegovy) and liraglutide (Saxenda)
Optimization and Plateau Considerations (Weeks 12-16+): After 12-16 weeks of use, the rate of body composition change may slow as users approach their genetic set points or as the body adapts metabolically
For this reason, people with a personal or family history of certain thyroid cancers are advised not to use these medications
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