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they not only "do what they do" - but impact downstream / analogous stream cascades where the likes of IL-6 & the metabolic form + feedback loops and inter-connected dependencies
Mounjaro is a dual agonist , meaning it activates two receptors: GLP1 receptor GIP receptor The UK SmPC also lays out how dosing usually works (start low and increase slowly): starting dose 2.5 mg once weekly, then move to 5 mg, then step up in 2.5 mg increments if needed (with at least 4 weeks at each step)
6 Adverse effects of GLP1-RA In contrast to the advantages of GLP-1RA the analogues have gastrointestinal side effects distinctly nausea, emesis and reduced appetite with lower risk of hypoglycemia compared to other glucose lowering drugs (110)
