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This is a biphasic (hormetic) dose-response common with copper peptides and many other biological compounds
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Isolation of PV1 and CAV20 BSO resistant mutants BSO-starved HeLa cells were infected with PV1-wt at a moi (multiplicity of infection) of 0.01 and incubated in the presence of BSO for 24 hr at which time partial CPE was observed
GHK-Cu (10 g/g) prevents LPS-induced decreases in lung superoxide dismutase (SOD) activity and glutathione (GSH) levels and reduces LPS-induced increases in the number of cells and the level of total protein in bronchoalveolar lavage fluid (BALF) in a mouse model of acute lung injury.Formal Name: [glycyl-kappaN-L-histidyl-kappaN,kappaN3-L-lysinato(2-)]-copper, monoacetate
