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This reinforces the need for carefully titrated regimens, especially in clinical settings where circadian timing (chronopharmacology) may dictate efficacy

It is the C-terminal tripeptide sequence of alpha-MSH, a naturally occurring peptide involved in inflammatory regulation and immune signaling

Additionally, ketamine is being used in the emergency department as an alternative to morphine for pain control and some paramedics are even administering ketamine in ambulances

After their eligibility was confirmed, the participants in both cohorts were then randomized 1:1 to receive LCLT supplement (Group A) or placebo (Group B) for 21 days in balanced blocks (Figure 1)