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Most patients find that the medication meaningfully reduces the effort required to maintain a healthy caloric deficit, and the nutrition coaching teaches them how to make that manageable long-term

They serve different purposes but can be used together for enhanced results

Notably, no serious ADRs were reported

However, studies support GLP-1RA to be cost effective in comparison to insulin therapy as per the healthcare models in high income countries while the parameter for comparison between the two include the increased risk of hypoglycaemia and all-cause mortality alongside emergency room visits and hospitalization